All Things Considered

Weekdays at 4-6:30 PM
  • Hosted by Melissa Block, Robert Siegel

Since its debut in 1971, this afternoon radio newsmagazine has delivered in-depth reporting and transformed the way listeners understand current events and view the world. Every weekday, hear two hours of breaking news mixed with compelling analysis, insightful commentaries, interviews, and special - sometimes quirky - features.  

Researchers in California described Wednesday their new method for mass-producing the key ingredient for the herbal drug artemisinin, the most powerful antimalarial on the market. Already, the French drugmaker Sanofi is ramping up production at a plant in Italy to manufacture the ingredient and the drug.

Global health advocates say they expect this new method of producing artemisinin will at last provide a stable supply of the drug and cut the overall cost of malaria treatment.

Scientists have come up with a new way to produce the most common anti-malaria medicine currently on the market and a French pharmaceutical company is opening a new plant this week to manufacture it. The synthetic version of artemisinin is expected to stabilize the malaria medicine market and reduce the overall cost of malaria treatment.

First lady Michelle Obama gave a personal and emotional speech Wednesday in Chicago as she stepped into the debate over gun control.

"Right now, my husband is fighting as hard as he can and engaging as many people as he can to pass common-sense reforms to protect our children from gun violence," she said.

The first lady was in her hometown to encourage business leaders to donate millions of dollars to programs for at-risk youth.

No one knows if Atlanta's school superintendent or any of the people accused of falsifying test results will go to jail, but they wouldn't be the first if they do.

Lorenzo Garcia, the former superintendent of schools in El Paso, Texas, has been sitting in a federal prison since last year. He's the nation's first superintendent convicted of fraud and reporting bogus test scores for financial gain.

On a normal day, Kansas City, Mo., processes more than 70 million gallons of raw sewage. This sewage used to be a nuisance, but Kansas City, and a lot of municipalities around the country, are now turning it into a resource for city farmers hard up for fertilizer.

After the sewage has been processed at a treatment plant, it's piped out to Birmingham Farm on the north side of the Missouri River.

It's no secret that many of the nation's roads are in pretty bad shape. In the latest report card from the American Society of Civil Engineers, the condition of America's highways rated a grade of D.

Congestion is a big problem, and so is upkeep. Most states rely on gas taxes to raise the money for repairs and new construction, but that funding source is not the stream it used to be, says James Corless of Transportation for America.

Since the November election, 240 California prisoners facing potential life sentences have been set free. That's because voters changed California's tough three strikes sentencing law.

As NPR reported in 2009, that law sent thousands of people to prison for terms of 25 years to life for minor, nonviolent crimes. Now those prisoners can ask the court to have their sentences reduced.

One of those set free under the new law is Shane Reams. He owes his freedom in no small part to his mother Sue's 17-year campaign to change the law.

For the first time in 14 years, Hugo Chavez is not on the ballot for a presidential election in Venezuela. The firebrand leftist died last month at 58 after a long fight with cancer.

Pollsters say the sympathy vote and the state's huge resources will translate into a big victory in Sunday's election for Chavez's hand-picked successor, Nicolas Maduro, a 50-year-old former bus driver turned government minister who had been a Chavez loyalist for 20 years.

University of Louisville fans have had a lot to cheer about lately — and not just basketball.

Monday's big victory by Louisville's men's basketball team over Michigan is just the latest success for the school and for an athletic department that is quickly becoming one of the country's most admired.

In January, the football team upset fourth-ranked Florida to win the Sugar Bowl, and coach Charlie Strong turned down a lucrative offer from the University of Tennessee to continue rebuilding the Louisville program.

A rat with some human genes could provide a better way to test Alzheimer's drugs.

The genetically modified rat is the first rodent model to exhibit the full range of brain changes found in Alzheimer's, researchers report in The Journal of Neuroscience.